Richards scored 14 of the Wildcats’ first 16 points, including a key 3-point play. Quickley’s 3 put Kentucky (10-3, 1-0) ahead for good.
Missouri (8-5, 0-1) cut a 16-point deficit down to 56-46 with 6:03 remaining. The Wildcats answered with a 6-0 spurt to help close it out.
Richards went 9 for 13 from the field and grabbed 12 rebounds for his second consecutive double-double. The junior forward also blocked four shots before fouling out with 3:52 left.
Quickley was 4 of 8 from behind the arc and 5 of 9 overall. He also went 9 for 9 at the line, part of a 27-for-30 performance for Kentucky as a team.
Kentucky guard Ashton Hagans left in the final minutes with a left ankle injury that coach John Calipari said was a low sprain.
Missouri: The Tigers’ quest for their first-ever Rupp Arena win began well enough as their defense aggressively denied inside chances while their shooters delivered from outside. That physical game also helped put Kentucky on the line often, resulting in a huge disparity on free throws. They didn’t have an answer for Richards, who was free on most of his opportunities.
Kentucky: The Wildcats started sluggishly from the field after a week off, missing six of seven shots while allowing the Tigers to make shots from deep. Richards was the steadying presence on both ends but especially with the ball, converting a pair of 3-point plays to keep them in the game before Quickley delivered from deep. Freshman guard Johnny Juzang missed the game with an illness, leaving them with just eight scholarship players.
Missouri hosts Tennessee on Tuesday night.
Kentucky visits Georgia on Tuesday night.